MicroSPECT-CT of Peripheral Angiogenesis

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Created 5/11/2010 5:00:00 AM

Hybrid microSPECT-CT images of peripheral angiogenesis in murine model of hindlimb ischemia. MicroCT images of bone structures and skin were registered with microSPECT images of Technetium-99m-labeled probe targeted at alpha-v beta-3 integrin expressed on proliferating endothelial cells to better demonstrate localization of the radiotracer within ischemic hindlimb (marked by yellow arrows).

Credits

• Wawrzyniec Lawrence Dobrucki , Yale University